VOPP1 Antibody, FITC conjugated
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中文名稱：VOPP1兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA03545C0Rb
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) VOPP1 Polyclonal antibody
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Uniprot No.：
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基因名：VOPP1
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別名：VOPP1 antibody; ECOP antibody; GASP antibody; Vesicular antibody; overexpressed in cancer antibody; prosurvival protein 1 antibody; EGFR-coamplified and overexpressed protein antibody; ECop antibody; Glioblastoma-amplified secreted protein antibody; Putative NF-kappa-B-activating protein 055N antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Vesicular, overexpressed in cancer, prosurvival protein 1 protein (23-172AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
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靶點詳情
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功能：Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
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基因功能參考文獻(xiàn)：
- miR-218 inhibits human lung adenocarcinoma cell migration and invasion via the suppression of Ecop and Robo1 expression PMID: 28936884
- Candidate gene eQTL showed a trans-acting association between variants of G protein-coupled receptor kinase 5 gene, previously linked to altered BB response, and high expression of VOPP1. PMID: 26860460
- VOPP1 is overexpressed in gastric adenocarcinoma, which is involved in promoting cell proliferation and migration and thus might serve as a putative oncogene. PMID: 25398664
- Upregulation of ECOP is associated with glioma. PMID: 23243056
- overexpression in cancer participates in the control of the intracellular redox state; its loss leads to oxidative cellular injury leading to cell death by the intrinsic apoptotic pathway PMID: 21519330
- ECOP was used as a molecular marker in patients with chronic wounds to guide surgical debridement. PMID: 17515955
- Results identify ECOP as a protein relevant to the biology of SCC. PMID: 19525979
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亞細(xì)胞定位：Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=When overexpressed, localizes in the nucleus and perinuclear regions.
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蛋白家族：VOPP1/ECOP family
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組織特異性：Widely expressed with highest levels in thymus and ovary.
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數(shù)據(jù)庫鏈接：
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