VDAC3 Antibody, FITC conjugated
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中文名稱：VDAC3兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA896484LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) VDAC3 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Voltage-dependent anion-selective channel protein 3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3), VDAC3
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Voltage-dependent anion-selective channel protein 3 protein (40-160aa)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
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基因功能參考文獻：
- The AG genotype of rs16891278 showed a significantly lower sperm concentration compared with the AA genotype (P = 0.044). Findings suggest that VDAC3 genetic variants may be associated with human sperm count. PMID: 28431403
- This cohort study showed that the VDAC3 gene was down regulation between patients with idiopathic Parkinson disease and controls PMID: 28916538
- VDAC3 is able to modulate its pore size and current by exploiting the mobility of the N-terminal and forming, upon external stimuli, disulfide bridges with cysteine residues located on the barrel and exposed to the inter-membrane space. PMID: 26806159
- channel gating of VDAC3 might be controlled by redox sensing under physiological conditions PMID: 26407725
- observed electrophysiological properties of hVDAC3 are surprisingly different from the other isoforms and are discussed in relation to the proposed physiological role of the protein in mammalian cells PMID: 25171321
- a VDAC3-Mps1 module at the centrosome promotes ciliary disassembly during cell cycle entry. PMID: 23388454
- VDAC3 is present at the mother centriole and modulates centriole assembly by recruiting Mps1 to centrosomes. PMID: 22935710
- VDAC3 has a limited ability to support mitochondrial respiration and has no influence in the control of ROS production. PMID: 20138821
- VDAC3 is a novel target for protein S-nigrosylation in spermatozoa. PMID: 17683036
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亞細胞定位：Mitochondrion outer membrane. Membrane.
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蛋白家族：Eukaryotic mitochondrial porin family
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組織特異性：Expressed in erythrocytes (at protein level). Widely expressed. Highest in testis.
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