USF2 Antibody
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中文名稱：USF2兔多克隆抗體
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貨號：CSB-PA621888LA01HU
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規(guī)格：￥440
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圖片：
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Western Blot
Positive WB detected in: Rat liver tissue
All lanes: USF2 antibody at 4.5μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 37, 31, 24 kDa
Observed band size: 37 kDa -
Immunofluorescence staining of MCF-7 cells with CSB-PA621888LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) USF2 Polyclonal antibody
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Uniprot No.：
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基因名：USF2
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別名：bHLHb12 antibody; Class B basic helix-loop-helix protein 12 antibody; FIP antibody; FOS interacting protein antibody; FOS-interacting protein antibody; Major late transcription factor 2 antibody; Upstream stimulatory factor 2 antibody; Upstream transcription factor 2 antibody; USF 2 antibody; Usf2 antibody; USF2_HUMAN antibody
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宿主：Rabbit
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反應(yīng)種屬：Human, Rat
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免疫原：Recombinant Human Upstream stimulatory factor 2 protein (21-162AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產(chǎn)品，USF2 Antibody (CSB-PA621888LA01HU)，的標記方式是Non-conjugated。對于USF2 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
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基因功能參考文獻：
- TCF21 modulates Steroidogenic factor-1 and estrogen receptor beta expression through the recruitment of USF2 in endometriotic stromal cells. PMID: 30018006
- USF2, and its target gene PAI-1, regulate serum-stimulated keratinocyte growth, and likely the cadence of cell cycle progression in replicatively competent cells as part of the injury repair program. PMID: 24905330
- RNA Pol II on HIF1 or HIF2 target genes is primarily associated with HIF1alpha or HIF2alpha in a STAT3 or USF2 dependent manner PMID: 23991099
- USF2 functionally interacts with YY1 blocking its inhibitory activity, in favor of CEBPB transactivation. PMID: 23560079
- USF2 and hypoxia-inducible factor 2alpha (HIF2alpha) cooperatively activate HIF2 target genes during hypoxia. PMID: 22966206
- Bone morphogenetic proteins and ID1 exerted an anti-apoptotic effect in mesangial cells by inhibition of USF2 transcriptional activity. PMID: 21921026
- data established that high glucose stimulated USF2 expression in HK-2 cells, at least in part, through angiotensin II-AT1-dependent activation of CREB, which can contribute to diabetic tubulointerstitial fibrosis PMID: 20814220
- Usf2 mediates quercetin-induced suppression of PAI-1 gene expression in human endothelial cells PMID: 20626032
- Ddata indicate that USF2 is one of the components of the FoxA1/androgen receptor transcriptional protein complex that contributes to the expression of androgen-regulated and prostate-specific genes. PMID: 19846536
- Unregulated activation of STAT-5, ERK1/2 and c-Fos may contribute to the phenotypic transformation from myelodysplastic syndrome to acute leukaemia. Impaired ERK1/2 signalling pathways were activated only by GM-CSF but not by Epo. PMID: 11583024
- defect in USF function may contribute to down-regulation of IGF2R expression in cancer cells. PMID: 12857727
- Cotransfection experiments demonstrated that overexpression of upstream stimulatory factor 2 increases cyclic GMP-dependent protein kinase I promoter activity in human vascular smooth muscle cells. PMID: 15741164
- USF1 and USF2 mRNA levels were reduced in non-small cell lung carcinoma; AP2-alpha levels were elevated; regression analysis demonstrated that reduced USF2 mRNA & increased AP2-alpha mRNA levels were predictive of downregulated PIGR mRNA expressions PMID: 15864740
- Data show that the elevated levels of USF2 in endometriosis account for, in part, the aberrant expression of SF-1 and its target gene StAR and aromatase. PMID: 18165439
- down-regulation of hsa-miR-10a may increase USF2 and contribute to the increase in cell proliferation of chronic myeloid leukemia implicating a miRNA in its abnormal behavior PMID: 19074828
- decreased expression of the Hint1 gene through epigenetic silencing may play a role in enhancing the growth of a subset of human hepatoma by increasing the expression of genes controlled by the transcription factors beta-catenin, USF2, and NFkappaB PMID: 19089909
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亞細胞定位：Nucleus.
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組織特異性：Ubiquitous.
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