UROD Antibody
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中文名稱：UROD兔多克隆抗體
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貨號：CSB-PA025678GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：UROD
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別名：DCUP_HUMAN antibody; PCT antibody; UPD antibody; URO D antibody; URO-D antibody; urod antibody; Uroporphyrinogen decarboxylase antibody; Uroporphyrinogen III decarboxylase antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human UROD
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
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基因功能參考文獻：
- a new mutation in the UROD gene in Egyptian patients with Hepatoerythropoietic porphyria, is reported. PMID: 26789143
- a new insight in the conformational changes occurred in the mutant structures of UROD protein. PMID: 24777812
- Data suggest that the traditional Chinese medicine (TCM) candidate potential three-in-one inhibitors for three drug target proteins epidermal growth factor receptor (EGFR), Her2, and uroporphyrinogen decarboxylase (UROD) against head and neck cancer. PMID: 23140436
- Expression of the D306Y mutation results in an insoluble recombinant protein. G318R and K297N have little effect on the structure or activity of recombinant URO-D, but the proteins display reduced stability in vitro. PMID: 19656450
- Among seventeen F-PCT patients, sixteen UROD mutations were identified. PMID: 23545314
- analysis of uroporphyrinogen decarboxylase as a potential target for specific components of traditional Chinese medicine PMID: 23209648
- Mutations in UROD gene is associated with familial porphyria cutanea tarda. PMID: 22382040
- Hepatoerythropoietic porphyria and familial porphyria cutanea tarda G281E mutation in the uroporphyrinogen decarboxylase gene PMID: 21079081
- function of Arg37 in uroporphyrinogen III decarboxylase PMID: 20553007
- description of 3 siblings with hepatoerythropoietic porphyria; sequencing of the UROD gene revealed compound heterozygosity for a novel missense mutation, V166A, and a complex deletion/insertion, 645del1053ins10 PMID: 20479301
- Sequence deletions in uroporphyrinogen decarboxylase is associated with Porphyria Cutanea Tarda. PMID: 15046048
- we identified eight mutations in 18 previously unclassified porphyria cutanea tarda families PMID: 15186324
- Sequencing of the hydroxymethylbilane synthase and uroporphyrinogen decarboxylase genes confirmed the relatively rare diagnosis of dual porphyria, and revealed a novel uroporphyrinogen decarboxylase mutation PMID: 16390615
- There is a high degree of molecular heterogeneity of familial porphyria cutanea tarda in Spain and molecular genetic analysis is useful in distinguish between F-PCT and sporadic PCT. PMID: 17627795
- role of UROD mutations as a strong risk factor for porphyria cutanea tarda even in areas where environmental factors (hepatitis C virus) have been shown to be highly associated with the disease PMID: 19419417
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相關疾病：Familial porphyria cutanea tarda (FPCT); Hepatoerythropoietic porphyria (HEP)
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亞細胞定位：Cytoplasm.
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蛋白家族：Uroporphyrinogen decarboxylase family
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數據庫鏈接：
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