UGGT2 Antibody

說明書

產品詳情

Uniprot No.：

Q9NYU1
基因名：

UGGT2
別名：

UGGT2 antibody; UGCGL2 antibody; UGT2UDP-glucose:glycoprotein glucosyltransferase 2 antibody; UGT2 antibody; hUGT2 antibody; EC 2.4.1.- antibody; UDP--Glc:glycoprotein glucosyltransferase 2 antibody; UDP-glucose ceramide glucosyltransferase-like 1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Human UGCGL2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
基因功能參考文獻：
1. In this study, we aimed to clarify the contribution of the noncatalytic domains by comparing activities of truncated forms of recombinant HUGT1/HUGT2 and HUGT1/HUGT2 chimeras with full-length enzymes. PMID: 27496766
2. The glucosyltransferase activity of UGGT2 has been lacking, leaving it unclear as to whether it has any function in the glycoprotein folding process. PMID: 24415556
3. HUGT2 cannot activate the catalytic domain of UDP-glucose: glycoprotein glucosyltransferase I PMID: 12913004
亞細胞定位：

Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
蛋白家族：

Glycosyltransferase 8 family
組織特異性：

Higher levels in kidney, pancreas, heart, and skeletal muscle.
數據庫鏈接：

HGNC: 15664

OMIM: 605898

KEGG: hsa:55757

STRING: 9606.ENSP00000365938

UniGene: Hs.193226

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