UBE2Q2 Antibody
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中文名稱：UBE2Q2兔多克隆抗體
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貨號(hào)：CSB-PA025475GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：UBE2Q2
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別名：LOC92912 antibody; UB2Q2_HUMAN antibody; UBE2Q2 antibody; Ubiquitin carrier protein Q2 antibody; Ubiquitin conjugating enzyme E2Q 2 antibody; Ubiquitin conjugating enzyme E2Q family member 2 antibody; Ubiquitin-conjugating enzyme E2 Q2 antibody; ubiquitin-conjugating enzyme E2Q (putative) 2 antibody; Ubiquitin-protein ligase Q2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human UBE2Q2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
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靶點(diǎn)詳情
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功能：Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination.
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基因功能參考文獻(xiàn)：
- UBE2Q1 hypomethylation is associated with Colorectal Cancer. PMID: 26745068
- The newly characterized human gene, UBE2Q2, may have implications for the pathogenesis of acute lymphoblastic leukemia. PMID: 22642244
- In the 21 breast cancer cases investigated, a high increase in UBE2Q2 expression was found in 8 breast cancers (38.1%), a moderately increased UBE2Q2 expression was observed in 7 cases (33.3%), and no sig. changes were detected in 6 cases (28.6%). PMID: 20193842
- Found high expression levels of UBE2Q2 in human head and neck carcinoma cell lines and cancer tissues; found the level of UBE2Q2 is decreased in cell lines and cancer tissues that have resistance to CDDP or docetaxel. PMID: 19723876
- the novel LOC92912 gene is characterized. It is over-expressed in hypopharyngeal tumours. Its functions may be linked with the cytoskeleton; it may represent a new target for cancer therapeutics. PMID: 16300736
- Inhibition of the UBE2Q2 protein causes cells to undergo a prolonged prophase arrest suggesting that UBE2Q2 normally functions to antagonize an early mitotic checkpoint. PMID: 17471241
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亞細(xì)胞定位：Cytoplasm.
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蛋白家族：Ubiquitin-conjugating enzyme family
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組織特異性：Detected in hypopharyngeal head and neck squamous cell carcinoma, in tumor masses and invasive epithelium.
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數(shù)據(jù)庫鏈接：
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