UBE2E3 Antibody, HRP conjugated
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中文名稱：UBE2E3兔多克隆抗體, HRP偶聯(lián)
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貨號(hào)：CSB-PA839280LB01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) UBE2E3 Polyclonal antibody
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Uniprot No.：
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基因名：UBE2E3
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別名：Homologous to yeast UBC4/5 antibody; UB2E3_HUMAN antibody; UBC E4 antibody; Ubc M2 antibody; UBC4/5 homolog antibody; UBCE 4 antibody; UBCE4 antibody; UBCH 9 antibody; UbcH9 antibody; UbcM2 antibody; UBE2 E3 antibody; UBE2E3 antibody; Ubiquitin carrier protein antibody; Ubiquitin carrier protein E3 antibody; Ubiquitin conjugating enzyme E2 23 kDa antibody; Ubiquitin conjugating enzyme E2 E3 antibody; Ubiquitin conjugating enzyme E2E 3 (homologous to yeast UBC4/5) antibody; Ubiquitin conjugating enzyme E2E 3 (UBC4/5 homolog, yeast antibody; Ubiquitin conjugating enzyme E2E 3 antibody; Ubiquitin conjugating enzyme UBCH 9 antibody; Ubiquitin conjugating enzyme UBCH9 antibody; Ubiquitin protein ligase antibody; Ubiquitin protein ligase E3 antibody; Ubiquitin-conjugating enzyme E2 E3 antibody; Ubiquitin-conjugating enzyme E2-23 kDa antibody; Ubiquitin-protein ligase E3 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Ubiquitin-conjugating enzyme E2 E3 protein (2-128AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
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基因功能參考文獻(xiàn)：
- Cells depleted of UBE2E3 become senescent in the absence of overt DNA damage and have a distinct senescence-associated secretory phenotype, increased mitochondrial and lysosomal mass, an increased sensitivity to mitochondrial and lysosomal poisons, and an increased basal autophagic flux. PMID: 29879550
- Data indicate that ubiquitin-conjugating enzyme UBE2E3 and importin 11 (Imp-11)promote the nuclear accumulation and activity of transcription factor NF-E2 (Nrf2) by restricting the transcription factor from partitioning to the mitochondria. PMID: 25378586
- UBE2E3 is essential for the proliferation of RPE-1 cells and is downregulated during RPE layer maturation in the developing mouse eye. PMID: 18614808
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亞細(xì)胞定位：Nucleus. Cytoplasm. Note=Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.
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蛋白家族：Ubiquitin-conjugating enzyme family
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組織特異性：Ubiquitously expressed at low levels. Highly expressed in skeletal muscle.
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數(shù)據(jù)庫鏈接：
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