UBAC2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) UBAC2 Polyclonal antibody
Uniprot No.：

Q8NBM4
基因名：

UBAC2
別名：

UBAC2; PHGDHL1; PSEC0110; Ubiquitin-associated domain-containing protein 2; UBA domain-containing protein 2; Phosphoglycerate dehydrogenase-like protein 1
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Ubiquitin-associated domain-containing protein 2 protein (1-157AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets. In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6.
基因功能參考文獻：
1. UBAC2 is associated with Behcet's disease in Chinese patients and implicates its involvement in transcriptional modulation. PMID: 22455605
2. We established and confirmed the genetic association between UBAC2 and Behcet's disease in 3 independent sets of patients and controls PMID: 21918955
3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
亞細胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein.
數據庫鏈接：

HGNC: 20486

KEGG: hsa:337867

STRING: 9606.ENSP00000383911

UniGene: Hs.508545

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