TXNL4A Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TXNL4A Polyclonal antibody
Uniprot No.：

P83876
基因名：

TXNL4A
別名：

TXNL4A antibody; DIM1 antibody; TXNL4Thioredoxin-like protein 4A antibody; DIM1 protein homolog antibody; Spliceosomal U5 snRNP-specific 15 kDa protein antibody; Thioredoxin-like U5 snRNP protein U5-15kD antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Thioredoxin-like protein 4A protein (1-142AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
基因功能參考文獻：
1. Recessive variants in TXNL4A were identified in two individuals with Burn-McKeown syndrome as well as in three individuals (from two families) with isolated choanal atresia. PMID: 28905882
2. Reporter gene and in vivo assays showed that the promoter deletions led to reduced expression of TXNL4A. Depletion of TXNL4A (Dib1) in yeast demonstrated reduced assembly of the tri-snRNP complex. PMID: 25434003
3. human dim1 is a peptidase with autocleavage activity that results in a thioredoxin-like core PMID: 17177886
相關疾病：

Burn-McKeown syndrome (BMKS)
亞細胞定位：

Nucleus.
蛋白家族：

DIM1 family
數據庫鏈接：

HGNC: 30551

OMIM: 608572

KEGG: hsa:10907

STRING: 9606.ENSP00000269601

UniGene: Hs.465498

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