Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Cytoplasmic protein that plays a role in the proper assembly of dynein arm complexes in motile cilia in both respiratory cells and sperm flagella.
基因功能參考文獻:
TTC12 SNP rs7130431 was associated with heroin dependence. PMID: 23303482
TTC12-ANKK1-DRD2s seemed to influence smoking behavior mainly in adolescence, and its effect is partially mediated by personality characteristics promoting drug-seeking behavior. PMID: 21168125
This study evaluated the interaction of ANKK1, TTC12, sex, and continental ancestry in tobacco smokers. PMID: 20133381
the TTC12 gene is hypermethylated in acute lymphoblastic leukemia PMID: 17657212
association studies of alcohol dependence and 43 SNPs mapped to the gene cluster of NCAM1, TTC12, ANKK1 and DRD2 PMID: 17761687
Genetic linkage tests conclude that variants in TTC12 exon 3 are involved in the regulation of risk for comorbid alcohol and drug dependence. PMID: 18828801
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亞細胞定位:
Cytoplasm.
組織特異性:
Expressed in testis and in epithelial cells of trachea and bronchial tube.