TRIT1 Antibody, FITC conjugated
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中文名稱：TRIT1兔多克隆抗體, FITC偶聯
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貨號：CSB-PA867142LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) TRIT1 Polyclonal antibody
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Uniprot No.：
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基因名：TRIT1
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別名：2310075G14Rik antibody; AI314189 antibody; AI314635 antibody; AV099619 antibody; FLJ20061 antibody; hGRO1 antibody; IPP transferase antibody; IPPT antibody; IPT antibody; IPTase antibody; Isopentenyl diphosphate:tRNA isopentenyltransferase antibody; Isopentenyl-diphosphate:tRNA isopentenyltransferase antibody; MGC149242 antibody; MGC149243 antibody; mitochondrial antibody; MOD5 antibody; MOD5_HUMAN antibody; OTTMUSP00000009314 antibody; Putative protein TR2IT1 antibody; RP23-121J14.6 antibody; TRIT 1 antibody; TRIT1 antibody; tRNA dimethylallyltransferase antibody; tRNA isopentenylpyrophosphate transferase antibody; tRNA isopentenyltransferase 1 antibody; tRNA isopentenyltransferase antibody; tRNA isopentenyltransferase mitochondrial antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human tRNA dimethylallyltransferase protein (1-324AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
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基因功能參考文獻：
- We show that dysfunctional TRIT1 results in decreased levels of select mitochondrial proteins. Our findings confirm the TRIT1 disease association and advance the phenotypic and molecular understanding of this disorder. PMID: 28185376
- characterize TRIT1 as a novel human amyloid fiber forming protein. We discuss these data in light of TRIT1's functional roles and possible implications for disease PMID: 27984194
- patient cells bearing the p.Arg323Gln TRIT1 mutation are severely deficient in i6A37 in both cytosolic and mitochondrial tRNAs PMID: 24901367
- In light of this additional nuclear role for Mod5 we discuss the proposed role of the human homologue of Mod5, TRIT1, as a tumor suppressor protein.[review] PMID: 25261850
- TRIT1 may control the levels of some tRNAs as well as their specific activity. PMID: 24126054
- One TRIT1 haplotype, CCGT, was associated with lymph node metastasis. PMID: 23349019
- The rare allele of TRIT1 Phe202Leu SNP was approximately seven-fold more frequent in Asian than in Caucasian subjects and three additional SNPs in the TRIT1 gene showed ethnic differences in allelic frequencies PMID: 17145094
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亞細胞定位：[Isoform 1]: Mitochondrion.; [Isoform 4]: Mitochondrion.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 5]: Cytoplasm.
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蛋白家族：IPP transferase family
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數據庫鏈接：
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