TRIM45 Antibody

中文名稱：

TRIM45兔多克隆抗體
貨號：

CSB-PA862044LA01HU
規(guī)格：

￥440
圖片：
IHC image of CSB-PA862044LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) TRIM45 Polyclonal antibody
Uniprot No.：

Q9H8W5
基因名：

TRIM45
別名：

FLJ13181 antibody; RING finger protein 99 antibody; RNF99 antibody; TRI45_HUMAN antibody; TRIM45 antibody; Tripartite motif containing 45 antibody; Tripartite motif containing protein 45 antibody; Tripartite motif-containing protein 45 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Tripartite motif-containing protein 45 protein (428-573AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產(chǎn)品，TRIM45 Antibody (CSB-PA862044LA01HU)，的標記方式是Non-conjugated。對于TRIM45 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA862044LB01HU	TRIM45 Antibody, HRP conjugated	ELISA
FITC	CSB-PA862044LC01HU	TRIM45 Antibody, FITC conjugated
Biotin	CSB-PA862044LD01HU	TRIM45 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.
基因功能參考文獻：
1. These findings suggest that TRIM45 is a novel tumor suppressor that stabilizes and activates p53 in glioma. PMID: 28542145
2. The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway. PMID: 24681954
3. These findings suggest that TRIM45 acts as a repressor for the NF-kappaB signal and regulates cell growth. PMID: 22634006
4. TRIM45 may act as a new transcriptional repressor in mitogen-activated protein kinase signaling pathway PMID: 15351693
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

TRIM/RBCC family
組織特異性：

Expressed in skeletal muscle, brain, heart and pancreas.
數(shù)據(jù)庫鏈接：

HGNC: 19018

OMIM: 609318

KEGG: hsa:80263

STRING: 9606.ENSP00000256649

UniGene: Hs.301526

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