TRIM44 Antibody
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中文名稱：TRIM44兔多克隆抗體
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貨號：CSB-PA024482GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：TRIM44
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別名：AN3 antibody; DIPB antibody; HSA249128 antibody; MC7 antibody; MGC3490 antibody; Protein DIPB antibody; TRI44_HUMAN antibody; TRIM44 antibody; Tripartite motif containing 44 antibody; Tripartite motif containing protein 44 antibody; Tripartite motif-containing protein 44 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human TRIM44
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May play a role in the process of differentiation and maturation of neuronal cells. May regulate the activity of TRIM17. Is a negative regulator of PAX6 expression.
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基因功能參考文獻：
- The levels of TRIM44 protein and TRIM44 mRNA in squamous cell carcinoma are both lowly expressed which is strongly associated with tumor staging, metastasis, and poor survival. PMID: 30383661
- Elevated TRIM44 expression promotes human esophageal cancer development by epithelial mesenchymal transition via the AKT/mTOR pathway. PMID: 30098109
- that TRIM44 predicts the risk of development and prognosis of endometrial cancer, highlighting its potential application as a therapeutic target for this malignancy PMID: 29526558
- Silencing of TRIM44 inhibits the proliferation, migration and invasion of papillary thyroid cancer cells. PMID: 28965013
- Mechanistic studies showed that knockdown of TRIM44 significantly reduced the levels of phosphorylated PI3K and Akt in PC-3 cells. Study provided evidence that knockdown of TRIM44 inhibited proliferation and invasion in prostate cancer cells, at least in part, through the inactivation of the PI3K/Akt signaling pathway. PMID: 28160462
- the TRIM44 status was an independent prognostic factor for distant disease-free survival (p = 0.005) and overall survival (p = 0.002) of patients. PMID: 28885545
- Data show that the TRIM44-mTOR axis increases metastasis and proliferation. PMID: 27058415
- These results suggest that tripartite motif-containing protein 44 protein could play a crucial role in tumor invasion through its overexpression and highlight its usefulness as a predictor and potential therapeutic target in esophageal squamous cell carcinoma PMID: 28618928
- results suggest that high expression of TRIM44 is associated with poor prognosis and that TRIM44 plays significant role in cell proliferation, migration, and anti-apoptosis in testicular germ cell tumor PMID: 27754579
- High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma. PMID: 27619678
- Variants in TRIM44 Cause Aniridia by Impairing PAX6 Expression PMID: 26394807
- Trim44 promotes non-small cell lung cancer development through activation of NF-kappaB signaling via upregulating CXCL16 and MMP9 expression. PMID: 25345539
- rim44 functions as a positive regulator of the virus-triggered immune response by enhancing the stability of VISA. PMID: 23460740
- Overexpression of the TRIM44 protein was significantly correlated with an advanced type of macroscopic appearance. PMID: 22862969
- terf interacts with TRIM44;TRIM44 inhibited ubiquitination of terf, and thus stabilized the protein. PMID: 19358823
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相關疾病：Aniridia 3 (AN3)
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組織特異性：Highly expressed in testis.
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數據庫鏈接：
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