Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
基因功能參考文獻:
TRIM proteins trim the balance of homoeostasis by modulating various biological pathways through protein-protein interactions. PMID: 23969027
MG53/TRIM72 protein can be directly applied as a therapeutic agent to increase membrane repair capacity of many cell types. PMID: 23699904
TRIM acts to chaperone CTLA-4 transport to the cell surface; this function would be required to account for the phenotypic and functional properties of CD8(+) Tregs. PMID: 18817831
亞細胞定位:
Cell membrane; Single-pass type III membrane protein.
組織特異性:
Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).