TRAM2 Antibody, Biotin conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) TRAM2 Polyclonal antibody
Uniprot No.：

Q15035
基因名：

TRAM2
別名：

TRAM2; KIAA0057; Translocating chain-associated membrane protein 2
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Translocating chain-associated membrane protein 2 protein (316-370AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
基因功能參考文獻：
1. TRAM2, as a part of the translocon, is required for the biosynthesis of type I collagen by coupling the activity of SERCA2b with the activity of the translocon PMID: 14749390
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

TRAM family
數(shù)據(jù)庫鏈接：

HGNC: 16855

OMIM: 608485

KEGG: hsa:9697

STRING: 9606.ENSP00000182527

UniGene: Hs.520182

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