TRA2A Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q13595
基因名：

TRA2A
別名：

AWMS1 antibody; HSU53209 antibody; htra-2 alpha antibody; Putative MAPK activating protein PM24 antibody; TRA 2 alpha antibody; TRA 2A antibody; TRA-2 alpha antibody; TRA2 alpha antibody; TRA2-alpha antibody; TRA2A antibody; TRA2A_HUMAN antibody; Tra2alpha antibody; Transformer 2 alpha antibody; Transformer 2 protein homolog antibody; Transformer-2 protein homolog A antibody; Transformer-2 protein homolog alpha antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human TRA2A
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.
基因功能參考文獻：
1. our findings suggest that paclitaxel targets the TRA2A-RSRC2 splicing pathway, and deregulated TRA2A and RSRC2 expression may confer paclitaxel resistance. In addition, our study demonstrates that expression of TRA2A in conjunction with RSRC2 may provide valuable molecular biomarker evidence for triple-negative breast cancer (TNBC)clinical treatment decisions and patient outcome PMID: 28416606
2. Overexpression of either Tra2alpha or Tra2beta results in a marked reduction in HIV-1 Gag/ Env expression. PMID: 25970345
3. findings show the inclusion of both HIV-1 exon 3 and vpr mRNA processing is promoted by an exonic splicing enhancer (ESEvpr) localized between exonic splicing silencer ESSV and 5'ss D3; the ESEvpr sequence was found to be bound by members of the Tra2 protein family PMID: 23255807
4. Expression of tumor-promoting Cyr61 is regulated by hTRA2-beta1 and acidosis. PMID: 21447598
亞細胞定位：

Nucleus.
蛋白家族：

Splicing factor SR family
數(shù)據(jù)庫鏈接：

HGNC: 16645

OMIM: 602718

KEGG: hsa:29896

STRING: 9606.ENSP00000297071

UniGene: Hs.445652

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