TOR Antibody

^{Rare Species}

說明書

中文名稱：

TOR Antibody
貨號：

CSB-PA861872XA01DOA
規格：

￥880
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) TOR Polyclonal antibody
Uniprot No.：

Q9FR53
基因名：

TOR
別名：

Serine/threonine-protein kinase TOR (EC 2.7.11.1) (Protein TARGET OF RAPAMYCIN) (AtTOR) TOR At1g50030 F2J10.19
宿主：

Rabbit
反應種屬：

Arabidopsis thaliana
免疫原：

Recombinant Arabidopsis thaliana TOR protein (40-59aa)
免疫原種屬：

Arabidopsis thaliana (Mouse-ear cress)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Essential cell growth regulator that controls development from early embryo to seed production. Controls plant growth in environmental stress conditions. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy. Can phosphorylate TAP46, a regulatory subunit of protein phosphatase 2A that modulates cell growth and survival. Involved in modulating the transition from heterotrophic to photoautotrophic growth by regulating the expression of chloroplast- and photosynthesis-associated genes. Essential for auxin signaling transduction, probably acting in polysomes to maintain the active ATPK1/S6K1 (and thus TIF3H1/eIF3h) phosphorylation status that is critical for translation reinitiation (e.g. uORF-mRNAs loading). Promotes abscisic acid (ABA) biosynthesis. Involved in the regulation of sugar-mediated (e.g. glucose and sucrose) glycolysis- and mitochondrial bioenergetics-dependent root growth promotion. Required for sugar (e.g. glucose) promotion of hypocotyl elongation in the dark, by activating the brassinosteroid pathway and stabilizing BZR1. The regulation of BZR1 degradation is dependent on autophagy. Regulates the expression, phosphorylation and ribosome association of MRFs (e.g. MRF1, MRF3 and MRF4), especially under energy-deficient conditions.; (Microbial infection) Binding to cauliflower mosaic virus (CaMV) Tav protein is critical for both translation reinitiation and viral fitness. When activated by CaMV P6, promotes CaMV translation by inhibiting cellular autophagy and suppressing both silencing and innate immunity, thus confering sensitivity to P.syringae.; (Microbial infection) Required during infection by some potyvirus such as Watermelon mosaic virus (WMV) but not for turnip mosaic virus (TuMV).
基因功能參考文獻：
1. Sugar-activated TOR kinase phosphorylates and stabilizes E2Fa proteins to transcriptionally activate S-phase genes during callus formation. PMID: 28623850
2. The dependence of potyviruses on active Arabidopsis TOR signalling was different. PMID: 25979731
3. These findings advance the current understanding of rapamycin-TOR signaling in plants. PMID: 23989449
4. highlight the possible role of TOR in carbon utilization and growth regulation in Arabidopsis PMID: 23761348
5. TOR protein regulates growth and also influences nutrient partitioning and central energy metabolism. PMID: 23173928
6. systems, cellular and genetic analyses uncover TOR phosphorylation of E2Fa transcription factor for an unconventional activation of S-phase genes, and glucose-signalling defects in e2fa root meristems PMID: 23542588
7. Rapamycin and glucose-target of rapamycin (TOR) protein signaling in plants. PMID: 22134914
8. The authors show that the function of Cauliflower mosaic virus viroplasmin in reinitiation depends on physical association with TOR, with viroplasmin-TOR binding being critical for both translation reinitiation and viral fitness. PMID: 21343906
9. TOR controls the embryogenesis, postembryonic development, and 45S rRNA production through its kinase domain in Arabidopsis. PMID: 21266656
10. Results provide evidence that TOR is a negative regulator of autophagy in plants. PMID: 20686696
11. The production of rapamycin-sensitive plants through the expression of baker's yeast FKBP12 protein illustrates the conservation of the TOR pathway in Arabidopsis. PMID: 17543119
12. The AtTOR kinase is one of the contributors to the link between environmental cues and growth processes in plants. PMID: 17721444
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亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

PI3/PI4-kinase family
組織特異性：

Highly expressed in root meristems, shoot apical meristem (SAM) and floral buds.
數據庫鏈接：

KEGG: ath:AT1G50030

STRING: 3702.AT1G50030.1

UniGene: At.16944

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