TOMM34 Antibody
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中文名稱：TOMM34兔多克隆抗體
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貨號：CSB-PA623014DSR2HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: TOMM34 antibody at 1.42µg/ml
Lane 1: Mouse gonadal tissue
Lane 2: A549 whole cell lysate
Lane 3: PC-3 whole cell lysate
Lane 4: A375 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 35 kDa
Observed band size: 35 kDa -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA623014DSR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA623014DSR2HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) TOMM34 Polyclonal antibody
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Uniprot No.：
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基因名：TOMM34
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別名：hTom34 antibody; HTOM34P antibody; Mitochondrial import receptor subunit TOM34 antibody; OTTHUMP00000031079 antibody; Outer mitochondrial membrane translocase (34kD) antibody; TOM 34 antibody; TOM34 antibody; TOM34_HUMAN antibody; TOMM 34 antibody; TOMM34 antibody; Translocase of outer membrane 34 kDa subunit antibody; Translocase of outer mitochondrial membrane 34 antibody; URCC 3 antibody; URCC3 antibody
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宿主：Rabbit
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反應種屬：Human, Mouse
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免疫原：Recombinant Human Mitochondrial import receptor subunit TOM34 protein (1-309AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state.
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基因功能參考文獻：
- Data show that Tomm34 extensively interacts with the C-terminal structures of Hsp70 selectively in its ATP-bound state and that this interaction is strongly entropically driven. PMID: 26944342
- These results suggest that Tomm34 represents a novel scaffolding co-chaperone of Hsp70 and Hsp90, which may facilitate Hsp70/Hsp90 cooperation during protein folding PMID: 24567332
- TOMM34 expression in early invasive breast cancer: a biomarker associated with poor outcome. PMID: 23053644
- Results identify Tom34 as a cochaperone of Hsp70/Hsp90 in mitochondrial protein import. PMID: 22178133
- Tom34 unlike Tom20 does not interact with the leader sequences of mitochondrial precursor proteins PMID: 11913975
- Yeast two-hybrid screening identifies binding partners of human Tom34 that have ATPase activity and form a complex with Tom34 in the cytosol PMID: 11913976
- TOMM34 is involved in the growth of colon cancer cells PMID: 16820880
- Data show that NRF-1 is the main transcription factor regulating the expression of TOMM34, and that Sp1 interacts with NRF-1 to stimulate the promoter's full activity. PMID: 18364745
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亞細胞定位：Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
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蛋白家族：Tom34 family
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組織特異性：Ubiquitous.
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數(shù)據(jù)庫鏈接：
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