TDRKH Antibody

說明書

產品詳情

Uniprot No.：

Q9Y2W6
基因名：

TDRKH
別名：

2700091C21Rik antibody; Putative RNA binding protein antibody; RGD1311196 antibody; RP11-98D18.8 antibody; TDRD2 antibody; TDRD7 antibody; Tdrkh antibody; TDRKH_HUMAN antibody; Tudor and KH domain containing antibody; Tudor and KH domain-containing protein antibody; tudor domain containing 2 antibody; Tudor domain-containing protein 2 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human TDRKH
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.
基因功能參考文獻：
1. Unlike most other Tudor domains TDRD2 preferentially recognizes an unmethylated arginine-rich sequence from PIWIL1. PMID: 29118143
2. Tudor domain proteins interact with arginine-glycine-rich motifs in a methylarginine-dependent manner. PMID: 15955813
亞細胞定位：

Cytoplasm. Mitochondrion.
蛋白家族：

Tdrkh family
數據庫鏈接：

HGNC: 11713

OMIM: 609501

KEGG: hsa:11022

STRING: 9606.ENSP00000357812

UniGene: Hs.144439

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