TDRD1 Antibody, Biotin conjugated
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中文名稱：TDRD1兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA874834LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) TDRD1 Polyclonal antibody
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Uniprot No.：
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基因名：TDRD1
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別名：Cancer/testis antigen 41.1 antibody; CT41.1 antibody; FLJ21082 antibody; MTR 1 antibody; TDRD 1 antibody; tdrd1 antibody; TDRD1_HUMAN antibody; Tudor domain containing 1 antibody; Tudor domain containing protein 1 antibody; Tudor domain-containing protein 1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Tudor domain-containing protein 1 protein (12-314AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins.
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基因功能參考文獻：
- TDRD1 protein is expressed in the majority of human prostate tumors, but not in normal prostate tissue. PMID: 27272765
- the involvement of TDRD1 genetic polymorphisms in piRNA processing genes in the risk of spermatogenic impairment in a Han Chinese population PMID: 27233649
- ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer. PMID: 23555854
- TDRD1 is the first identified upregulated direct ERG target gene that is strongly associated with ERG overexpression in primary prostate cancer PMID: 23319146
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亞細胞定位：Cytoplasm.
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蛋白家族：TDRD1 family
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組織特異性：Testis and ovary specific. Also expressed in several cancers.
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數據庫鏈接：
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