Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
May be required for cellular fusion during osteoclastogenesis.
基因功能參考文獻:
TCTA protein has roles in lung cancer cell lines and human osteoclastogenesis [review] PMID: 22174563
It expressed in synovial tissues from patients with RA and inhibits human osteoclastogenesis. (review) PMID: 20046013
TCTA is a novel protein expressed in synovial tissues of rheumatoid arthritis that regulate human osteoclastogenesis. PMID: 19560569
相關疾?。?/div>
A chromosomal aberration involving TCTA is associated with T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(1;3)(p34;p21).
亞細胞定位:
Membrane; Multi-pass membrane protein.
蛋白家族:
TCTA family
組織特異性:
Ubiquitous. Highest level of expression in kidney. Present in monocytes, osteoclasts, macrophages, synoviocytes and synovial lining cells (at protein level).