TCN1 Antibody, FITC conjugated
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中文名稱：TCN1兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA023317LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) TCN1 Polyclonal antibody
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Uniprot No.：
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基因名：TCN1
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別名：Haptocorin antibody; Haptocorrin antibody; HC antibody; OTTHUMP00000235879 antibody; TC 1 antibody; TC I antibody; TC-1 antibody; TC1 antibody; TCI antibody; TCN 1 antibody; TCN1 antibody; TCO1_HUMAN antibody; Transcobalamin 1 antibody; Transcobalamin I antibody; Transcobalamin-1 antibody; Transcobalamin1 antibody; TranscobalaminI antibody; Vitamin B12 binding protein antibody; Vitamin B12 binding protein R binder family antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Transcobalamin-1 protein (24-433AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
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靶點詳情
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功能：Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
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基因功能參考文獻：
- Higher placental TC protein abundance was associated with higher cord blood vitamin B12 concentrations, suggesting a potential role in vitamin B12 transport to the fetus. PMID: 27577703
- The variant rs526934 from the TCN1 gene was associated with an increased risk of developing gastric cancer. PMID: 26959381
- Levels of holotranscobalamin are decreased patients with cobalamin deficiency. PMID: 24057896
- Structural basis for universal corrinoid recognition by the cobalamin transport protein haptocorrin. PMID: 23846701
- TCN1 gene expression implicates disease progression in patient with middle ear cholesteatoma. PMID: 23670528
- comparison of human and rainbow trout cobalamin-binding protein PMID: 22872637
- Elevated concentrations of B(12) found in autoimmune lymphoproliferative syndrome patients were due to increased lymphocyte expression of haptocorrin. PMID: 22306884
- Stromal expression of KRT15, TCN1, and HOXB13 was significantly correlated with tumor grade, stromal hypercellularity, mitotic activity and microscopic borders. PMID: 21574054
- two novel mutations, each causing a premature stop codon - a genetic basis for TC I deficiency PMID: 19686235
- Comparative analysis of cobalamin binding kinetics PMID: 11788601
- No association between the MTHFR A1298C and transcobalamin C776G genetic polymorphisms and hyperhomocysteinemia in thrombotic disease. PMID: 12590948
- interactions of COBALAMIN BINDING proteins with a number of ligands PMID: 17487979
- Maternal folate-related polymorphisms studied here (CBS, MTR, RFC-1, and TC) have no influence on trisomy 21 susceptibility in subjects of Brazilian population.v PMID: 19729796
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亞細胞定位：Secreted.
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蛋白家族：Eukaryotic cobalamin transport proteins family
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組織特異性：Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils.
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數(shù)據(jù)庫鏈接：
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