TBKBP1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TBKBP1 Polyclonal antibody
Uniprot No.：

A7MCY6
基因名：

TBKBP1
別名：

KIAA0775 antibody; ProSAPiP2 antibody; SINTBAD antibody; TANK binding kinase 1 binding protein 1 antibody; TANK-binding kinase 1-binding protein 1 antibody; TBK1 binding protein 1 antibody; TBK1-binding protein 1 antibody; TBKB1_HUMAN antibody; Tbkbp1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human TANK-binding kinase 1-binding protein 1 protein (327-427AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
基因功能參考文獻：
1. The two selected single nucleotide polymorphisms (SNPs) in TBKBP1 show no relationship with the clinical outcomes. None of the 12 SNPs is related to mSASSS. PMID: 25494292
2. TBKBP1 is associated with the severity of ankylosing spondylitis in the Chinese Han population PMID: 23637848
3. Studies show that three proteins expressed in HEK-293T cells (NAP1, TANK and TBKBP1) interact with TBK1. PMID: 23286385
4. results suggest that efficient signal transduction upon viral infection requires SINTBAD, TANK and NAP1 because they link TBK1 and IKKi to virus-activated signalling cascades PMID: 17568778
組織特異性：

Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
數據庫鏈接：

HGNC: 30140

OMIM: 608476

KEGG: hsa:9755

STRING: 9606.ENSP00000354777

UniGene: Hs.94790

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