TBC1D15 Antibody, FITC conjugated
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中文名稱：TBC1D15兔多克隆抗體, FITC偶聯
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貨號：CSB-PA823452LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) TBC1D15 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：DKFZp686M1379 antibody; DKFZp761D0223 antibody; FLJ12085 antibody; FLJ33191 antibody; GAP for RAB7 antibody; GTPase-activating protein RAB7 antibody; RAB7 GAP antibody; Rab7-GAP antibody; TBC1 domain family member 15 antibody; TBC15_HUMAN antibody; Tbc1d15 antibody; Tre 2 budding uninhibited by benzimidazole cell division cycle 16 domain; domain family member 15 antibody; Tre2/Bub2/Cdc16 domain family member 15 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human TBC1 domain family member 15 protein (283-404AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6.
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基因功能參考文獻：
- Report provides evidence for a new function of TBC1D15 in the control of GLUT4 vesicles translocation through regulating Rab7 activity. Glucose uptake was greatly reduced when TBC1D15 was knocked out. PMID: 30316925
- Demonstrate that TBC1D15 and TBC1D17 mediate proper autophagic encapsulation of mitochondria by regulating Rab7 activity at the interface between mitochondria and isolation membranes. PMID: 24569479
- TBC1D15 is required for the accumulation of RhoA. PMID: 24337944
- Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology. PMID: 23077178
- although only TBC1D15/Rab7-GAP altered Rab7-GTP levels, both Rab7-GAP and mVps39 regulate lysosomal morphology and play a role in maintaining growth factor dependence PMID: 20363736
- This paper primarily describes mouse TBC1D15 but also reports the primary structure of human TBC1D15. PMID: 16055087
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亞細胞定位：Cytoplasm.
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數據庫鏈接：
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