SYT6 Antibody

中文名稱：

SYT6兔多克隆抗體
貨號：

CSB-PA716356LA01HU
規格：

￥440
圖片：
Immunofluorescence staining of MCF-7 cells with CSB-PA716356LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SYT6 Polyclonal antibody
Uniprot No.：

Q5T7P8
基因名：

SYT6
別名：

Synaptotagmin 6 antibody; Synaptotagmin VI antibody; Synaptotagmin-6 antibody; Synaptotagmin6 antibody; SynaptotagminVI antibody; Syt 6 antibody; Syt VI antibody; SYT6 antibody; SYT6_HUMAN antibody; SytVI antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Synaptotagmin-6 protein (104-425AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，SYT6 Antibody (CSB-PA716356LA01HU)，的標記方式是Non-conjugated。對于SYT6 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA716356LB01HU	SYT6 Antibody, HRP conjugated	ELISA
FITC	CSB-PA716356LC01HU	SYT6 Antibody, FITC conjugated
Biotin	CSB-PA716356LD01HU	SYT6 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm.
基因功能參考文獻：
1. synaptotagmin must be dephosphorylated at a specific window of time and phosphorylated synaptotagmin has an active role at early stages of the acrosomal exocytosis. PMID: 20551332
2. Acrosomal exocytosis is regulated through the PKC-mediated phosphorylation of conserved threonines in the polybasic regions of synaptotagmin VI. PMID: 16111671
3. SYT6 is hypermethylated in renal cell carcinoma. PMID: 18639284
亞細胞定位：

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.; [Isoform 1]: Membrane; Single-pass membrane protein.; [Isoform 2]: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein.
蛋白家族：

Synaptotagmin family
數據庫鏈接：

HGNC: 18638

OMIM: 607718

KEGG: hsa:148281

STRING: 9606.ENSP00000358559

UniGene: Hs.370963

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