SUGCT Antibody

說明書

產品詳情

Uniprot No.：

Q9HAC7
基因名：

SUGCT
別名：

SUGCT antibody; C7orf10 antibody; DERP13 antibody; Succinate--hydroxymethylglutarate CoA-transferase antibody; EC 2.8.3.13 antibody; Dermal papilla-derived protein 13 antibody; SuccinylCoA:glutarate-CoA transferase antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human C7orf10
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate.
基因功能參考文獻：
1. Chromosome microarray analysis showed a 125kb homozygous pathogenic deletion, which includes genes MPLKIP and SUGCT, not described before. This is the first case described in Peru of a novel contiguous gene deletion of Trichothiodystrophy type 4 and Glutaric aciduria type 3 performed by chromosome microarray analysis. PMID: 29421601
2. C7orf10 encodes succinate-hydroxymethylglutarate CoA-transferase, which is the enzyme that converts glutarate to glutaryl-CoA PMID: 23893049
3. Identified as a candidate disease gene for OXPHOS disorders by next-generation sequencing PMID: 22277967
4. Geneic mapping of GA3 to chromosome 7 and identification of mutations in c7orf10 are reported. PMID: 18926513
相關疾?。?/div>
Glutaric aciduria 3 (GA3)
亞細胞定位：

Mitochondrion.
蛋白家族：

CaiB/BaiF CoA-transferase family
組織特異性：

Highly expressed in kidney. Intermediate expression in liver, skeletal muscle and pancreas. Little to no expression detected in other tissues examined.
數據庫鏈接：

HGNC: 16001

OMIM: 231690

KEGG: hsa:79783

UniGene: Hs.586313

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