STOM Antibody
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中文名稱：STOM兔多克隆抗體
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貨號(hào)：CSB-PA022862GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：BND7 antibody; EPB7 antibody; EPB72 antibody; Erythrocyte band 7 integral membrane protein antibody; Erythrocyte membrane protein band 7.2 (stomatin) antibody; Erythrocyte surface protein band 7.2 antibody; Protein 7.2b antibody; STOM antibody; STOM_HUMAN antibody; Stomatin antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Human STOM
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.
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基因功能參考文獻(xiàn)：
- we show that stomatin modulates the transport activity of AE1 through a direct protein-protein interaction. PMID: 28387307
- These results may suggest that stomatin is a new prognostic indicator for HER2-positive breast cancer PMID: 27577936
- FRAP analyses indicate that the stomatin C-terminus is the dominant entity for lateral mobility and binding site for the cortical actin cytoskeleton PMID: 28575093
- This study showed that cells expressing more stomatin or exposed to exogenous stomatin are more prone to undergoing cell fusion; during osteoclastogenesis, depletion of stomatin inhibited cell fusion but had little effect on tartrate-resistant acid phosphatase production. PMID: 27663861
- Authors took a proteomic approach to identify stomatin, a member of the integral proteins of lipid rafts, as a cellular protein interacting with hepatitis C virus NS5B. PMID: 25262680
- Stomatin protein expression is down-regulated in 80% of non-small cell lung cancer samples. PMID: 24533441
- upregulation of stomatin by hypoxia and dex may enhance the barrier function of alveolar epithelia and mediate the adaptive role of glucocorticoid to hypoxia PMID: 23672602
- Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains PMID: 23219802
- [review] Stomatin family member STOM is oligomeric; it localizes mostly to membrane domains and has been shown to modulate ion channel activity. PMID: 21501885
- The study indicates that stomatin, sorcin, and synexin are echinophilic membrane components that mainly locate outside GM1 rafts in the human erythrocyte membrane. PMID: 20858460
- This study demonstrated the existence of alpha-granular lipid rafts and suggests an important role for stomatin in the organization and function of alpha granules. PMID: 12130500
- stomatin is localized to detergent-insoluble domains of neutrophil granule membranes PMID: 12429719
- in stomatocytosis there is no significant abnormality in stomatin gene sequence instead, deficiency of stomatin from red cells appears to be due to a loss of stomatin from these red cells on maturation in the bone marrow and in the circulation. PMID: 12750157
- study of strongly homologous stomatin-like genes in prokaryotes reveals a close connection with a gene coding for a hydrophobic protein with a probable serine protease motif; stomatin could be a partner protein for a membrane-bound proteolytic process PMID: 15121101
- stomatin binds to and alters the gating of acid-sensing ion channels PMID: 15471860
- A small C-terminal region of stomatin that is largely hydrophobic (residues 264-272) is crucial for oligomerization, whereas the N-terminal domain (residues 1-20) and the last 12 C-terminal amino acids (residues 276-287) are not essential. PMID: 16766530
- The stomatin-actin association is important in maintaining the structure and in modulating the function of stomatin-containing membrane rafts in red cells. PMID: 17961506
- Data indicate that a stomatin-specific, raft-based process is involved in storage-associated vesiculation. PMID: 18067507
- Stomatin-like protein-1 interacts with stomatin and is targeted to late endosomes PMID: 19696025
- Stomatin is a member of an ancient protein family that has extremely well conserved homologues in all three domains of life. PMID: 18267007
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亞細(xì)胞定位：Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle.
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蛋白家族：Band 7/mec-2 family
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組織特異性：Detected in erythrocytes (at protein level). Widely expressed.
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數(shù)據(jù)庫(kù)鏈接：
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