STEAP2 Antibody
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中文名稱：STEAP2兔多克隆抗體
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貨號：CSB-PA275156
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規格：￥2024
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圖片：
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using STEA2 antibody. -
Immunofluorescence analysis of A549 cells, using STEA2 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) STEAP2 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：STEAP2; PCANAP1; STAMP1; UNQ6507/PRO23203; Metalloreductase STEAP2; Prostate cancer-associated protein 1; Protein up-regulated in metastatic prostate cancer; PUMPCn; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane protein of prostate 1
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from C-terminal of Human STEA2.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：ELISA,IHC,IF
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推薦稀釋比：
Application Recommended Dilution IHC 1:50-1:100 IF 1:100-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.
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基因功能參考文獻：
- Over-expression of STEAP2 is associated with prostate cancer progression. PMID: 25248617
- Data suggest that STAMP1 is required for prostate cancer growth. PMID: 20587517
- Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
- cloning and characterization of STAMP1, which is expressed in both normal prostate and prostate neoplasms PMID: 12095985
- STEAP2 is involved in the development of prostate cancer. As a cell-surface antigen, it is a potential diagnostic or therapeutic target in prostate cancer. PMID: 12429817
- Expression of STAMP2, a gene highly similar to STAMP1 (STEAP2), in prostate cancer cells significantly increases cell growth and colony formation suggesting that STAMP2 may have a role in cell proliferation. PMID: 15897894
- STEAPs may represent novel markers of mesenchymal stem cells in man as well as mice. PMID: 19196137
- The murine ortholog, Steap2, is a ferrireductase, cupric reductase, and stimulates cellular uptake of both iron and copper in vitro. PMID: 16609065
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亞細胞定位：Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
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蛋白家族：STEAP family
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組織特異性：Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.
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數據庫鏈接：
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