ST6GALNAC1 Antibody

中文名稱：

ST6GALNAC1兔多克隆抗體
貨號：

CSB-PA868312LA01HU
規格：

￥440
圖片：
Western Blot
Positive WB detected in: HepG2 whole cell lysate
All lanes: ST6GALNAC1 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 69 kDa
Observed band size: 69 kDa

Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA868312LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA868312LA01HU at dilution of 1:100
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ST6GALNAC1 Polyclonal antibody
Uniprot No.：

Q9NSC7
基因名：

ST6GALNAC1
別名：

6-sialyltransferase 1 antibody; 6-sialyltransferase I antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase antibody; Alpha-N-acetylgalactosaminide alpha-2 antibody; GalNAc alpha 2 6 sialyltransferase I antibody; GalNAc alpha-2 antibody; HSY11339 antibody; SIA7A_HUMAN antibody; Sialyltransferase 7A antibody; SIAT7-A antibody; SIAT7A antibody; ST6 (alpha N acetyl neuraminyl 2 3 beta galactosyl 1 3) N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; ST6GalNAc I antibody; ST6GALNAC1 antibody; ST6GalNAcI antibody; STYI antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 protein (36-249AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，ST6GALNAC1 Antibody (CSB-PA868312LA01HU)，的標記方式是Non-conjugated。對于ST6GALNAC1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA868312LB01HU	ST6GALNAC1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA868312LC01HU	ST6GALNAC1 Antibody, FITC conjugated
Biotin	CSB-PA868312LD01HU	ST6GALNAC1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

基因功能參考文獻：
1. Our results indicated that ST6GALNAC1 was downregulated in sporadic esophageal squamous cell carcinoma via hyper-methylation and loss of heterozygosity , and it may be a candidate responsible gene for esophageal squamous cell carcinoma PMID: 28035351
2. ST6GalNAc I regulates the gene expression of IGF-1 through STAT5b activation and plays role in gastric cancer invasion and metastasis. PMID: 25532910
3. upregulated Siat7A expression, which was paralleled by the increased Klf4 in the ischemic myocardium, contributed to cardiomyocyte apoptosis following myocardial infarction PMID: 25860962
4. Using qRT-PCR, sialyl-Tn expression was found to be associated with an increase in alpha2,6-sialyltransferase gene (ST6GALNAC1) and a decrease in core 1 synthase gene (C1GALT1) in LS174T cells. PMID: 24840470
5. It was confirmed that MUC1 carries sialyl Tn also in human advanced gastric cancer tissues PMID: 22228572
6. The stable transfection of MDA-MB-231 with an expression vector encoding ST6GalNAc I induces the expression of STn antigen at the cell surface. PMID: 12820722
7. ST6GalNAc-I sialyltransferase localizes throughout the Golgi and has a role in synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer PMID: 16319059
8. Expression of ppGalNAc-T6 is significantly higher in breast cancer compared to 'normal'/benign breast tissue samples. ST6GalNAc-I expression in breast cancer is associated with better prognosis. PMID: 19287074
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亞細胞定位：

Golgi apparatus membrane; Single-pass type II membrane protein.
蛋白家族：

Glycosyltransferase 29 family
數據庫鏈接：

HGNC: 23614

OMIM: 610138

KEGG: hsa:55808

STRING: 9606.ENSP00000156626

UniGene: Hs.105352

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