SRSF11 Antibody

說明書

產品詳情

Uniprot No.：

Q05519
基因名：

SRSF11
別名：

Arginine rich 54 kDa nuclear protein antibody; Arginine-rich 54 kDa nuclear protein antibody; arginine/serine-rich 11 antibody; dJ677H15.2 antibody; DKFZp686M13204 antibody; NET2 antibody; P54 antibody; Serine/arginine-rich splicing factor 11 antibody; SFR11 antibody; SFRS 11 antibody; Splicing factor antibody; Splicing factor arginine/serine rich 11 antibody; Splicing factor p54 antibody; SRS11_HUMAN antibody; SRSF11 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the Internal region of Human SFRS11.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May function in pre-mRNA splicing.
基因功能參考文獻：
1. 1p31 SFRS11 v PMID: 24657192
2. SRp54 interacts with a purine-rich element tau in exon 10 and antagonizes Tra2beta, an SR-domain-containing protein that enhances exon 10 inclusion. PMID: 16943417
3. The G2/M arrest induced by MIAs is required for p54(nrb) phosphorylation. CDK activity is required for MIA-induced phosphorylation of p54(nrb). PMID: 18832053
亞細胞定位：

Nucleus. Note=Colocalizes with spliceosome components.
蛋白家族：

Splicing factor SR family
數據庫鏈接：

HGNC: 10782

OMIM: 602010

KEGG: hsa:9295

STRING: 9606.ENSP00000359988

UniGene: Hs.479693

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