SMC1B Antibody
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中文名稱：SMC1B兔多克隆抗體
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貨號：CSB-PA854104LA01HU
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規格：￥440
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圖片：
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IHC image of CSB-PA854104LA01HU diluted at 1:400 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. -
IHC image of CSB-PA854104LA01HU diluted at 1:400 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SMC1B Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：bK268H5 antibody; SMC protein 1B antibody; SMC-1-beta antibody; SMC-1B antibody; SMC1 beta antibody; SMC1B antibody; SMC1B_HUMAN antibody; SMC1beta antibody; SMC1beta protein antibody; Smc1l2 antibody; Structural maintenance of chromosomes 1-like 2 antibody; Structural maintenance of chromosomes 1B antibody; Structural maintenance of chromosomes protein 1B antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Structural maintenance of chromosomes protein 1B protein (954-1060AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，SMC1B Antibody (CSB-PA854104LA01HU)，的標記方式是Non-conjugated。對于SMC1B Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:200-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
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基因功能參考文獻：
- Through the translational regulation of novel RNA targets SMC1B and TEX11, DAZL may have a key role in regulating chromosome cohesion and DNA recombination; two processes fundamental in determining oocyte quality and whose establishment in foetal life may support lifelong fertility. PMID: 28364521
- Data show that structural maintenance of chromosomes protein 1B (SMC1B) is expressed in primary fibroblasts. PMID: 26673124
- High SMC1B expression is associated with pancreatic cancer. PMID: 25216700
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亞細胞定位：Nucleus. Chromosome. Chromosome, centromere.
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蛋白家族：SMC family, SMC1 subfamily
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數據庫鏈接：
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