SLC6A12 Antibody
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中文名稱：SLC6A12兔多克隆抗體
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貨號：CSB-PA021690ESR2HU
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規(guī)格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA021690ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA021690ESR2HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) SLC6A12 Polyclonal antibody
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Uniprot No.：
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基因名：SLC6A12
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別名：Betaine/GABA transporter 1 antibody; BGT-1 antibody; BGT1 antibody; Gamma aminobutyric acid transporter antibody; GAT2 antibody; Na(+)/Cl(-) betaine/GABA transporter antibody; S6A12_HUMAN antibody; Slc6a12 antibody; Sodium- and chloride-dependent betaine transporter antibody; Solute carrier family 6 (neurotransmitter transporter), member 12 antibody; Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 antibody; Solute carrier family 6 member 12 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Sodium- and chloride-dependent betaine transporter protein (515-614AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
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基因功能參考文獻(xiàn)：
- The SLC6A12 expression levels in peripheral blood mononuclear cells were significantly higher in TLE patients. PMID: 26690518
- T40 may be important for the trafficking and insertion of BGT1 in the plasma membrane PMID: 24829506
- JAK2 is a novel regulator of the GABA transporter BGT1. PMID: 22405821
- This study found that rs216250 of SLC6A12 was correlated with the Scale for the Assessment of Negative Symptoms (SANS) scores. PMID: 21367462
- Results showed that two polymorphisms and a haplotype in SLC6A12, were significantly associated with AIA after multiple testing corrections. PMID: 20597903
- The primary structure of BGT-1 predicts two putative phosphorylation sites for the Ca2+/diacylglycerol-dependent protein kinase (PKC), which regulates BGT-1 function by phosphorylation events in a transport system expressed in cultured astrocytoma cells. PMID: 12111824
- BGT-1 is expressed from mRNA and transports GABA in platelets. PMID: 16198020
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亞細(xì)胞定位：Membrane; Multi-pass membrane protein.
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蛋白家族：Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A12 subfamily
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組織特異性：Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.
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數(shù)據(jù)庫鏈接：
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