SLC35C1 Antibody
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中文名稱：SLC35C1兔多克隆抗體
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貨號：CSB-PA839285LA01HU
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規格：￥440
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圖片：
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IHC image of CSB-PA839285LA01HU diluted at 1:400 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SLC35C1 Polyclonal antibody
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Uniprot No.：
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基因名：SLC35C1
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別名：SLC35C1 antibody; FUCT1GDP-fucose transporter 1 antibody; Solute carrier family 35 member C1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human GDP-fucose transporter 1 protein (287-364AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，SLC35C1 Antibody (CSB-PA839285LA01HU)，的標記方式是Non-conjugated。對于SLC35C1 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:200-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.
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基因功能參考文獻：
- two Turkish siblings with a novel mutation in GDP-fucose transporter and features of congenital disorder of glycosylation IIc PMID: 25239688
- Fx enzyme and GDP-L-Fuc Tr overexpression in the tumur tissue of colorectal cancer (CRC) patients suggests that GDP-L-Fuc transport to the Golgi apparatus may be an important factor associated with increased alpha(1,6)fucosylation in CRC. PMID: 23730929
- In the rare LAD-II disease, the fucosylation of selectin ligands is disturbed, caused by mutations in SLC35C1, the gene that encodes a GDP-fucose transporter of the Golgi system. (Review) PMID: 22134107
- the conserved glycine residues at positions 180 and 277 of SLC35C1 have significant impacts on lectin binding PMID: 22492235
- In the GDP-fucose transporter a new single nucleotide deletion produced an open-reading frame shift & polypeptide truncation. Overexpression of the mutant protein in fibroblasts did not rescue fucosylation. The deletion ablated transporter activity. PMID: 12406889
- Leukocyte adhesion deficiency II patients display dual defect in functoin ang Golgi expression of FUCT1. PMID: 16455955
- the upregulation of GDP-Fuc Tr plays a pivotal role in increased fucosylation in hepatocellular carcinoma PMID: 17884843
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相關疾?。?/div>Congenital disorder of glycosylation 2C (CDG2C)亞細胞定位：Golgi apparatus membrane; Multi-pass membrane protein.蛋白家族：TPT transporter family, SLC35C subfamily數據庫鏈接：
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