SLC31A2 Antibody, HRP conjugated
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中文名稱：SLC31A2兔多克隆抗體, HRP偶聯(lián)
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貨號：CSB-PA021577LB01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) SLC31A2 Polyclonal antibody
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Uniprot No.：
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基因名：SLC31A2
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別名：SLC31A2; COPT2; CTR2; Probable low affinity copper uptake protein 2; Copper transporter 2; hCTR2; Solute carrier family 31 member 2
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Probable low affinity copper uptake protein 2 protein (44-93AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Involved in low-affinity copper uptake.
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基因功能參考文獻(xiàn)：
- 11 single-nucleotide polymorphisms (SNPs) in CTR1, CTR2, ATP7A, and ATP7B were genotyped in these patients. PMID: 28737129
- Decreased expression of CTR2 is associated with clear cell renal cell carcinoma. PMID: 26411550
- Over-expression of CTR2 increased exchangeable Cu(+) by 150% and rendered the human epithelial 2008 cancer cell model 2.5-fold resistant to cisplatin. PMID: 24522273
- Increased CTR2 expression is associated with platinum resistance in epithelial ovarian cancer. PMID: 23564780
- hCTR2 is as an oligomeric membrane protein localized in lysosomes, which stimulates copper delivery to the cytosol of human cells at relatively high copper concentrations. PMID: 17617060
- Ctr2 promotes copper uptake at the plasma membrane and plays a role in regulating copper levels in COS-7 cells PMID: 17944601
- CTR2 functions by limiting drug accumulation, and its expression correlates with the sensitivity of human ovarian carcinoma cell lines to cisplatin. PMID: 19509135
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亞細(xì)胞定位：Membrane; Multi-pass membrane protein.
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蛋白家族：Copper transporter (Ctr) (TC 1.A.56) family, SLC31A subfamily
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組織特異性：Ubiquitous.
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數(shù)據(jù)庫鏈接：
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