SLC25A37 Antibody

中文名稱：

SLC25A37兔多克隆抗體
貨號：

CSB-PA873700LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA873700LA01HU diluted at 1:200 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SLC25A37 Polyclonal antibody
Uniprot No.：

Q9NYZ2
基因名：

SLC25A37
別名：

SLC25A37; MFRN; MSCP; HT015; Mitoferrin-1; Mitochondrial iron transporter 1; Mitochondrial solute carrier protein; Solute carrier family 25 member 37
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Mitoferrin-1 protein (1-44AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，SLC25A37 Antibody (CSB-PA873700LA01HU)，的標記方式是Non-conjugated。對于SLC25A37 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA873700LB01HU	SLC25A37 Antibody, HRP conjugated	ELISA
FITC	CSB-PA873700LC01HU	SLC25A37 Antibody, FITC conjugated
Biotin	CSB-PA873700LD01HU	SLC25A37 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme.
基因功能參考文獻：
1. The findings of this study implicate that the SCL25A37 is a major depressive disorder susceptibility gene whose expression may influence major depressive disorder risk. PMID: 27643475
2. Data show that abnormal MFRN1 expression can contribute to erythropoietic protoporphyria phenotype in some patients, probably by causing a reduction in FECH activity. PMID: 21627978
3. hypoxia induces the expression of mitoferrin mRNAs through separate mechanisms in erythroid cells PMID: 19187226
亞細胞定位：

Mitochondrion inner membrane; Multi-pass membrane protein.
蛋白家族：

Mitochondrial carrier (TC 2.A.29) family
數據庫鏈接：

HGNC: 29786

OMIM: 610387

KEGG: hsa:51312

STRING: 9606.ENSP00000429200

UniGene: Hs.596025

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