SLC16A3 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SLC16A3 Polyclonal antibody
Uniprot No.：

O15427
基因名：

SLC16A3
別名：

MCT 4 antibody; MCT3 antibody; MCT4 antibody; Monocarboxylate transporter 3 antibody; Monocarboxylate transporter 4 antibody; MOT4_HUMAN antibody; SLC16A3 antibody; Solute carrier family 16 member 3 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Monocarboxylate transporter 4 protein (406-465AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
基因功能參考文獻：
1. MCT1 may be acting as an uptake transporter and MCT4 as an efflux system across the basolateral membrane for ferulic acid, and that this process is stimulated by butyric acid. PMID: 26854723
2. Ocular absorption of monocarboxylic acid drugs may be enhanced by MCT transporter SLC16A3, and the absorption route provided by the transporter may be utilized to improve the bioavailability of topically applied ophthalmic drugs. PMID: 20035863
3. Gamma-hydroxybutyric acid (GHB) is a substrate for both MCT2 and MCT4. PMID: 17502341
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family
組織特異性：

Highly expressed in skeletal muscle.
數據庫鏈接：

HGNC: 10924

OMIM: 603877

KEGG: hsa:9123

STRING: 9606.ENSP00000376150

UniGene: Hs.500761

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