SLC16A11 Antibody
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中文名稱：SLC16A11兔多克隆抗體
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貨號：CSB-PA808680
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規(guī)格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA808680(SLC16A11 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA808680(SLC16A11 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200) -
Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA808680(SLC16A11 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 2 minutes
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：FLJ90193 antibody; MCT 11 antibody; Monocarboxylate transporter 11 antibody; MOT11_HUMAN antibody; SLC16A11 antibody; Solute carrier family 16 member 11 (monocarboxylic acid transporter 11) antibody; Solute carrier family 16 member 11 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse
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免疫原：Synthetic peptide of Human SLC16A11
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Proton-linked monocarboxylate transporter. It catalyzes the transport of pyruvate across the plasma membrane. Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, small increases in intracellular diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids.
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基因功能參考文獻(xiàn)：
- rs13342232 might be involved in the risk of pediatric-onset type 2 diabetes in Mexican families PMID: 28101933
- Study demonstrates that disruption of SLC16A11 in primary human hepatocytes leads to Type 2 diabetes (T2D)-relevant changes in fatty acid and lipid metabolism; these results implicate reduced SLC16A11 function in liver as a causal factor for T2D. PMID: 28666119
- Our study identified an association between the SLC16A11 variant rs75493593 and type 2 diabetes in American Indians, where the effect on diabetes was much more pronounced in nonobese individuals. rs75493593 was also associated with RNASEK gene expression. PMID: 26487785
- Genetic association studies show that common variants in ABCA1 and SLC16A11 are involved in type 2 diabetes (T2D) susceptibility. Particularly, the variants rs10811661 (CDKN2A/2B) and rs9282541 (ABCA1) are associated with T2D in adult Maya population. PMID: 25839936
- Despite type 2 diabetes having been well studied by GWAS in other populations, analysis in Mexican and Latin American individuals identified SLC16A11 as a novel candidate gene for type 2 diabetes with a possible role in triacylglycerol metabolism. PMID: 24390345
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相關(guān)疾病：Diabetes mellitus, non-insulin-dependent (NIDDM)
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亞細(xì)胞定位：Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
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蛋白家族：Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family
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組織特異性：Expressed in liver, salivary gland and thyroid.
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數(shù)據(jù)庫鏈接：
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