SGCB Antibody, HRP conjugated
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中文名稱：SGCB兔多克隆抗體, HRP偶聯
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貨號：CSB-PA618082LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SGCB Polyclonal antibody
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Uniprot No.：
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基因名：SGCB
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別名：43 kDa dystrophin associated glycoprotein antibody; 43 kDa dystrophin-associated glycoprotein antibody; 43DAG antibody; A3b antibody; Beta SG antibody; Beta-sarcoglycan antibody; Beta-SG antibody; dystrophin-associated glycoprotein, 43-kD antibody; LGMD2E antibody; Limb girdle muscular dystrophy 2E (non linked families) antibody; Sarcoglycan beta antibody; sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) antibody; SGC antibody; SGCB antibody; SGCB_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Beta-sarcoglycan protein (124-219AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
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基因功能參考文獻：
- This study demonstrated that LGMD2E is the most common type of sarcoglycanopathies in the Iranian population. PMID: 28687063
- Clinical severity of limb-girdle muscular dystrophy type 2Emay be predicted by SGCB gene mutation and sarcoglycan protein expression. PMID: 25862795
- Defective assembly of sarcoglycan complex in patients with beta-sarcoglycan gene mutations PMID: 12060343
- beta-sarcoglycan and SPATA18 may have a role in limb-girdle muscular dystrophy type 2E PMID: 16088906
- While the quantity of beta-sarcoglycan was nearly normal in the limb girdle muscular dystrophy (LGMD)2E carrier, the levels of dysferlin protein were reduced to 50% of controls in the carriers of LGMD2B. PMID: 16934466
- These data suggest that formation of the beta-delta-core may promote the export and deposition of sarcoglycan subcomplexes at the plasma membrane, and therefore identifies a mechanism for sarcoglycan transport. PMID: 17036316
- The limb-girdle muscular dystrophy patients with beta-sarcoglycan deficient LGMD2E do not enable an accurate prediction of the genotype. PMID: 18996010
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相關疾病：Limb-girdle muscular dystrophy 2E (LGMD2E)
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亞細胞定位：Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton.
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蛋白家族：Sarcoglycan beta/delta/gamma/zeta family
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組織特異性：Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver.
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數據庫鏈接：
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