SEPT6 Antibody
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中文名稱：SEPT6兔多克隆抗體
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貨號：CSB-PA246269
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規(guī)格：￥2024
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圖片：
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Western blot analysis of extracts from Jurkat cells, using SEPT6 antibody. -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using SEPT6 antibody.
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) SEPT6 Polyclonal antibody
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Uniprot No.：
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基因名：SEPT6
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Synthesized peptide derived from internal of Human SEPT6.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 IHC 1:50-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
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基因功能參考文獻(xiàn)：
- Results demonstrate that in stored platelets, septine-2 and septin-6 mRNAs have miR- 223 target sites, septin-2 and septin-6 are in complex with Ago-2. The results demonstrate that like in nucleated cells, enucleated platelets also have microRNA-based mechanisms for the regulation of their septins. PMID: 29943706
- SUMOylation of human septins is critical for septin filament bundling and cytokinesis. PMID: 29051266
- MiR-223-3p might target gene SEPT6 and promoted the biological behavior of prostate cancer. PMID: 25519054
- Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis PMID: 25380047
- The SEPT6 provides the directional guidance cues necessary for polarizing the epithelial microtubule network. PMID: 21788367
- Data show that Septins of the SEPT6 group preferentially interacted with septins of the SEPT2 group, SEPT3 group and SEPT7 group. PMID: 21082023
- MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia PMID: 12096348
- Molecular analysis using rtPCR followed by sequencing confirmed the expression of an MLL-SEPT6 fusion transcript with a novel sequence. PMID: 16843108
- septin 2, 6, and 7 complexes make up polymerized filaments PMID: 16914550
- These results indicate that the host proteins hnRNP A1 and septin 6 play important roles in the replication of HCV through RNA-protein and protein-protein interactions. PMID: 17229681
- crystal structures of the human SEPT2 G domain and the heterotrimeric human SEPT2-SEPT6-SEPT7 complex PMID: 17637674
- Demonstrate connection between septins/SOCS7/NCK signaling and the DNA damage response. PMID: 17803907
- co-expression of SEPT12 altered the filamentous structure of SEPT6 in Hela cells PMID: 18047794
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亞細(xì)胞定位：Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cleavage furrow. Midbody. Cell projection, cilium, flagellum.
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蛋白家族：TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
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組織特異性：Widely expressed.
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數(shù)據(jù)庫鏈接：
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