SEPT5 Antibody

說明書

產品詳情

Uniprot No.：

Q99719
基因名：

SEPT5
別名：

5 Sep antibody; CDCrel 1 antibody; CDCREL antibody; CDCrel-1 antibody; CDCREL1 antibody; Cell division control related protein 1 antibody; Cell division control-related protein 1 antibody; H5 antibody; HCDCREL 1 antibody; OTTHUMP00000197271 antibody; OTTHUMP00000197272 antibody; OTTHUMP00000197273 antibody; OTTHUMP00000197274 antibody; OTTHUMP00000197275 antibody; OTTHUMP00000197276 antibody; OTTHUMP00000197396 antibody; OTTHUMP00000197410 antibody; Peanut like 1 antibody; Peanut like 1 homolog antibody; Peanut like protein 1 antibody; Peanut-like protein 1 antibody; Platelet glycoprotein Ib beta chain antibody; PNUTL1 antibody; SEPT5 antibody; SEPT5_HUMAN antibody; Septin 5 antibody; Septin-5 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the Internal region of Human Septin 5.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion.
基因功能參考文獻：
1. CDCrel-1 overexpression exerts dopamine-dependent neurotoxicity and may contribute to the development of autosomal-recessive juvenile parkinsonism PMID: 14530399
2. We studied the assembly of three human septins, SEPT4, SEPT5 and SEPT8, with each other (heterotypic) and with themselves (homotypic) using a yeast two-hybrid system. PMID: 15214843
3. the high expression levels of PNUTL1 in human pancreatic endocrine cells that suggests a similar role of this protein in islet cells to that demonstrated in neuronal tissues, and warrants further functional studies of this protein. PMID: 16179808
4. Our finding suggests a role for members of the septin family in the development of proliferative retinal membranes. PMID: 17625225
5. HSP70 and constitutively active HSF1 mediate protection against CDCrel-1-mediated toxicity PMID: 18398426
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亞細胞定位：

Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules.
蛋白家族：

TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
組織特異性：

Expressed at high levels in the CNS, as well as in heart and platelets (at protein level).
數據庫鏈接：

HGNC: 9164

OMIM: 602724

KEGG: hsa:5413

STRING: 9606.ENSP00000391311

UniGene: Hs.728762

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