SCGB2A1 Antibody
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中文名稱：SCGB2A1兔多克隆抗體
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貨號(hào)：CSB-PA003188
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規(guī)格：￥1090
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圖片：
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Western Blot analysis of HepG2 cells using Mammaglobin B Polyclonal Antibody
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：SCGB2A1
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別名：Lacryglobin antibody; LIPHC antibody; Lipophilin C antibody; Lipophilin-C antibody; LPHC antibody; LPNC antibody; Mammaglobin 2 antibody; Mammaglobin-2 antibody; Mammaglobin-B antibody; MGB2 antibody; MGC71973 antibody; Scgb2a1 antibody; Secretoglobin family 2A member 1 antibody; Secretoglobin; family 2A; member 1 antibody; SG2A1_HUMAN antibody; UGB3 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Synthesized peptide derived from the N-terminal region of Human Mammaglobin B.
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：WB, IHC, IF, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.
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基因功能參考文獻(xiàn)：
- The expression of HOXB13, IL17BR, and mammaglobin 1 in sentinel lymph nodes predict the outcome of primary breast cancer patients. PMID: 29729704
- novel marker GATA3 stains a significantly higher proportion of both primary and metastatic breast carcinomas than GCDFP15 or mammaglobin with stronger and more diffuse staining, helpful in cases with small tissue samples PMID: 25906123
- The commonly used breast carcinoma biomarkers vary in their prognostic implications. GCDFP-15 independently indicated a favourable prognosis. GATA-3 and MGB were not associated with outcome. PMID: 25425335
- Results indicate that the quantitative analysis of h-MAM mRNA is a useful tool for detecting CTCs in breast cancer patients. PMID: 24706379
- Results indicated that SCGB2A1 represented a novel, prognostic factor for colorectal cancer, and its expression correlated with chemoresistance, radioresistance and cancer cell stemness. PMID: 24585249
- The data indicate that MGB1, MGB2 and LIPB mRNAs are expressed at low levels in human tissues but basal expression is upregulated in ovarian cancer. PMID: 24603286
- SCGB2A1 is a top differentially expressed gene in all major histological types of ovarian cancers. PMID: 23807163
- MGB has the highest expression in HER2-overexpressing breast cancers and may be a potentially useful marker for this subtype. PMID: 23332923
- Data show that plasma mammaglobin mRNA alone or in combination with CA15.3 (CD227) may be used as a valuable noninvasive approach for the diagnosis and the detection of metastasis in breast cancer at the time of diagnosis. PMID: 20306663
- The mammaglobin/lipophilin B complex is a promising diagnostic marker for breast cancer. PMID: 12022875
- MGB2 markers may be useful for identifying micrometastases in sentinel lymph nodes of breast cancer patients. PMID: 15151203
- SCGB 2A1 represents a new class of androgen target genes that are purely under indirect AR control mediated by DNA-bound Sp factors. PMID: 16020486
- Results indicate that mammaglobin, as measured by the ELISA, holds significant promise for breast cancer screening with the realistic potential to impact management of this disease. PMID: 16166429
- MGB-2 is highly expressed in endometrioid endometrial cancer [EEC], particularly in well- and moderately differentiated tumors, and may represent a novel molecular marker for EEC PMID: 18021217
- Expression levels of mammaglobins A and B in nasal polyps are not different between patients with and without AR PMID: 18416968
- MGB-2 expression characterizes less aggressive forms of EOC and is correlated with a favorable outcome PMID: 19635143
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亞細(xì)胞定位：Secreted.
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蛋白家族：Secretoglobin family, Lipophilin subfamily
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組織特異性：Expressed in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland.
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數(shù)據(jù)庫(kù)鏈接：
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