SCARF1 Antibody

說明書

產品詳情

Uniprot No.：

Q14162
基因名：

SCARF1
別名：

Acetyl LDL receptor antibody; Endothelial cells scavenger receptor antibody; SCARF1 antibody; Scavenger receptor class F member 1 antibody; Scavenger receptor expressed by endothelial cells 1 antibody; Scavenger receptor expressed by endothelial cells antibody; SREC antibody; SREC-I antibody; SREC_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human SCARF1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth.
基因功能參考文獻：
1. Scavenger receptor SREC-I promotes double stranded RNA-mediated TLR3 activation in human monocytes PMID: 25641411
2. These studies in addition to our earlier findings showed SREC-I to play a primary role in chaperone-associated antigen uptake both through cross priming of MHC class I molecules and entry into the class II pathway. PMID: 25155057
3. In several assay systems this type F-scavenger receptor, termed SREC-I, bound to cell wall techoic acid in a charge dependent manner and mediated adhesion to nasal epithelial cells in vitro. PMID: 24788600
4. GP2 is a binding partner of the scavenger receptor expressed on endothelial cells I (SREC-I) but not of SR-AI and SR-BI. Dendritic cells express SREC-I and also bind and internalize GP2. PMID: 21190681
5. Characterization of the gene and its regulation by a novel transcription factor, endothelial zinc protein-2 PMID: 11978792
6. SRECI binds to SRECII and has a similar tissue distribution pattern PMID: 12154095
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亞細胞定位：

Membrane; Single-pass type I membrane protein.
組織特異性：

Endothelial cells.
數據庫鏈接：

HGNC: 16820

OMIM: 607873

KEGG: hsa:8578

STRING: 9606.ENSP00000263071

UniGene: Hs.647430

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