SAMSN1 Antibody, FITC conjugated
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中文名稱：SAMSN1兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA885722LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) SAMSN1 Polyclonal antibody
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Uniprot No.：
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基因名：SAMSN1
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別名：HACS1 antibody; Hematopoietic adapter containing SH3 and sterile α, motif (SAM) domains 1 antibody; Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1 antibody; Hematopoietic adaptor containing SH3 and SAM domains 1 antibody; Nash1 antibody; Nuclear localization signals SAM and SH3 domain containing 1 antibody; SAM and SH3 domain containing 2 antibody; SAM domain antibody; SAM domain containing protein SAMSN 1 antibody; SAM domain SH3 domain and nuclear localisation signals 1 antibody; SAM domain SH3 domain and nuclear localization signals 1 antibody; SAM domain, SH3 domain and nuclear localization signals protein 1 antibody; SAM domain-containing protein SAMSN-1 antibody; SAMN1_HUMAN antibody; SAMSN 1 antibody; Samsn1 antibody; SASH2 antibody; SH3 domain and nuclear localisation signals 1 antibody; SH3 domain and nuclear localization signals protein 1 antibody; SH3 SAM adaptor protein antibody; SH3-SAM adaptor protein antibody; SH3D6B antibody; SLy2 antibody; Src homology domain 3 (SH3) containing adapter protein SH3 lymphocyte protein 2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human SAM domain-containing protein SAMSN-1 protein (1-373AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation.
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基因功能參考文獻：
- Suppression of SAMSN1 Expression is Associated with the Malignant Phenotype of Hepatocellular Carcinoma. PMID: 25805236
- This is the first study to identify deletion of a key gene in the C57BL/KaLwRij mice that also displays reduced gene expression in patients with MM and is therefore likely to play an integral role in MM disease development. PMID: 25117979
- High expression of SAMSN1 is a significant risk factor for the progression free and overall survival of glioblastoma multiforme PMID: 24278465
- the immunoinhibitory roles of SLy2 in vivo and suggest that the physiological up-regulation of SLy2 observed upon B cell activation functions to counteract excessive B cell spreading. PMID: 21296879
- In the nucleus, SLy2 interacts with the SAP30/HDAC1 complex and regulates the activity of HDAC1. PMID: 20478393
- HACS1 is up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. PMID: 15381729
- downregulation of SAMSN1 gene in human lung cancer. PMID: 18523997
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亞細胞定位：Nucleus. Cytoplasm. Cell projection, ruffle.
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組織特異性：Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.
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數(shù)據(jù)庫鏈接：
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