S100A3 Antibody

說明書

中文名稱：

S100A3兔多克隆抗體
貨號：

CSB-PA020631ESR2HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA020631ESR2HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) S100A3 Polyclonal antibody
Uniprot No.：

P33764
基因名：

S100A3
別名：

Protein S 100E antibody; Protein S-100E antibody; Protein S100 A3 antibody; Protein S100-A3 antibody; S100 calcium binding protein A3 antibody; S100 calcium-binding protein A3 antibody; S100a3 antibody; S100E antibody; S10A3_HUMAN antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Protein S100-A3 protein (1-101AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
基因功能參考文獻(xiàn)：
1. S100A3 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
2. One disulfide bridge is between Cys30 in the N-terminal pseudo-EF-hand and Cys68 in the C-terminal EF-hand (SS1), and another disulfide bridge attaches Cys99 in the C-terminal coil structure to Cys81 in helix IV (SS2). PMID: 21377473
3. crystal structure of S100A3 at 1.7-A resolution PMID: 12045193
4. structure was solved by MIRAS phasing PMID: 12136135
5. Purification and characterization of the S100A3 protein from human hair cuticles. PMID: 12470658
6. cytoplasmic S100A3 within the cuticular layer is mostly co-localized with the type III isoform of peptidylarginine deiminase (PAD3) PMID: 18083705
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亞細(xì)胞定位：

Cytoplasm.
蛋白家族：

S-100 family
組織特異性：

Skin specific, specifically expressed at the inner endocuticle of hair fibers.
數(shù)據(jù)庫鏈接：

HGNC: 10493

OMIM: 176992

KEGG: hsa:6274

STRING: 9606.ENSP00000357701

UniGene: Hs.557609

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