RXRG Antibody
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中文名稱：RXRG兔多克隆抗體
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貨號：CSB-PA020614GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：MGC109416 antibody; NR2B3 antibody; Nuclear receptor subfamily 2 group B member 3 antibody; OTTHUMP00000060418 antibody; Retanoic X receptor gamma antibody; Retinoic acid receptor RXR gamma antibody; Retinoic acid receptor RXR-gamma antibody; Retinoid X receptor gamma antibody; RXR G antibody; RXR gamma antibody; RXRC antibody; Rxrg antibody; RXRG_HUMAN antibody; RXRgamma antibody
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反應種屬：Human,Mouse,Rat
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免疫原：Human RXRG
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid.
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基因功能參考文獻：
- genetic association studies in a population in Brazil: Data suggest that SNPs in RXRG (rs2134095) and GC (rs7041) are associated with low-density lipoprotein cholesterol levels and hypercholesterolemia in the population studied; there was no apparent association with an SNP in VDR (rs2228570). (RXRG = retinoid X receptor gamma; GC = vitamin D-binding protein; VDR = vitamin D receptor) PMID: 27721113
- Germline mutations in the RXRG gene are linked to Familial isolated pituitary adenoma in a Brazilian Family. PMID: 27245436
- Data show that some rexinoids display selective coactivator (CoA) recruitment by the retinoid X receptors (RXRs) homodimer and by the heterodimers nuclear receptor Nur77/RXR and Nurr1/RXR. PMID: 26148973
- loss of RXR-gamma levels appears to provide mechanistic benefits to transformed cells towards the acquisition of resistance to apoptosis hallmark of cancer PMID: 23936423
- Genetic variation in RXRgamma gene may contribute to the development of HIVLD in combination antiretroviral therapy treated HIV patients. PMID: 23759678
- The RXR-gamma rs3818569 single nucleotide polymorphisms is associated with diabetic retinopathy development in the Taiwanese population. PMID: 22180072
- results indicate that RXR-gamma is a positive regulator of endogenous oligodendrocyte precursor cell differentiation and remyelination. PMID: 21131950
- methylation-associated downregulation of the RXRG gene may play a differential role in the carcinogenesis of non-small cell lung cancer (NSCLC) according to smoking status. PMID: 20113835
- Single nucleotide polymorphism not a factor in resistance to thyroid hormone. PMID: 15186611
- The retinoid X receptor, gamma expression is mainly restricted to the muscle and brain. PMID: 15608692
- These results show that the stimulation of ASCT2 expression in response to glutamine in part involves binding of FXR/RXR to the ASCT2 promoter. PMID: 16197915
- RXRgamma contributes to the genetic background of familial combined hyperlipidemia. PMID: 17272748
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亞細胞定位：Nucleus. Cytoplasm.
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蛋白家族：Nuclear hormone receptor family, NR2 subfamily
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組織特異性：Expressed in aortic endothelial cells (at protein level).
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數據庫鏈接：
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