RSU1 Antibody
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中文名稱：RSU1兔多克隆抗體
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貨號：CSB-PA020558GA01HU
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規(guī)格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：RSU1
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別名：FLJ31034 antibody; Ras suppressor protein 1 antibody; Ras suppressor protein 1 isoform 1 antibody; RSP 1 antibody; RSP-1 antibody; RSP1 antibody; RSU 1 antibody; Rsu-1 antibody; RSU1 antibody; RSU1 protein antibody; RSU1_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human RSU1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro.
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基因功能參考文獻：
- our results indicate the important role of RSU-1 in BC metastasis and set the foundations for its validation as potential BC metastasis marker. PMID: 28423706
- Ras suppressor protein 1 was confirmed to be directly targeted by miR-409-5p in breast cancer cells. Small interfering RNA-mediated Ras suppressor protein 1 inhibition reversely promoted cancer proliferation and migration in miR-409-5p-downregualted breast cancer cells. MiR-409-5p is downregulated in breast cancer and its inhibition has anti-cancer effect on breast cancer development both in vitro and in vivo. PMID: 28459205
- Rsu1 is required for EGF-induced activation of the p38 map kinase signaling PMID: 25482629
- integrin/Rsu1/Rac1/actin signaling has a conserved role in modulating reward-related phenotypes, including ethanol consumption, across phyla PMID: 26170296
- Upregulation of RSU1 is associated with metastatic breast cancer. PMID: 25647720
- results showed that RSU-1 expression is elevated in HepG2 cells both at the mRNA and protein level PMID: 25750304
- alternative splicing of exon 8 of the RSU-1 RNA to produce the exon-deleted form constitutes a mechanism for reduction or loss of functional Rsu-1. The exon-deleted form was not found in normal tissue. PMID: 12510772
- Rsu-1 links the Ras pathway with the IPP (integrin-linked kinase {ILK}, PINCH-1/LIMS1, parvin) complex and the perturbations of cell attachment-dependent signaling that occur in the malignant process PMID: 18436335
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