RPL35A Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RPL35A Polyclonal antibody
Uniprot No.：

P18077
基因名：

RPL35A
別名：

60S ribosomal protein L35a antibody; Cell growth-inhibiting gene 33 protein antibody; DBA5 antibody; L35A antibody; Ribosomal Protein L35a antibody; RL35A_HUMAN antibody; RPL35A antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human 60S ribosomal protein L35a (1-110AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.
基因功能參考文獻：
1. We identified 85 overlapping deletions, of which six included the RPL35A gene and all should be had Diamond-Blackfan anemia (DBA).we sequenced the remaining RNF168 gene and examined her fibroblast culture for a DNA double strand break repair deficiency. These results were normal, indicating that the immunodeficiency is unlikely to result from a RNF168 deficiency. PMID: 28432740
2. Studies identified deletions at known Diamond-Blackfan anemia (DBA)-related ribosomal protein gene loci in 17% (9 of 51) of patients without an identifiable mutation, including RPS19, RPS17, RPS26, and RPL35A. PMID: 22045982
3. Inhibition of cell death by ribosomal protein L35a. PMID: 12175552
4. analysis of 2 Diamond-Blackfan anemia (DBA) patients with chromosome 3q deletions identified RPL35A as a potential DBA gene PMID: 18535205
相關疾病：

Diamond-Blackfan anemia 5 (DBA5)
蛋白家族：

Eukaryotic ribosomal protein eL33 family
數據庫鏈接：

HGNC: 10345

OMIM: 180468

KEGG: hsa:6165

STRING: 9606.ENSP00000393393

UniGene: Hs.529631

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