RPL3 Antibody
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中文名稱：RPL3兔多克隆抗體
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貨號：CSB-PA003985
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規格：￥1090
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圖片：
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Western Blot analysis of HT29 cells using Ribosomal Protein L3 Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：RPL3
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別名：60S ribosomal protein L3 antibody; HIV-1 TAR RNA-binding protein B antibody; HIV1 TAR RNA binding protein B antibody; MGC103388 antibody; MGC104284 antibody; MGC72934 antibody; Ribosomal protein L3 antibody; Ribosomal protein L3, isoform a antibody; RL3_HUMAN antibody; rpl3 antibody; TARBP B antibody; TARBP-B antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from the Internal region of Human Ribosomal Protein L3.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
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基因功能參考文獻：
- The sensitivity of p53 null colon cancer cells to 5-FU can be enhanced using proapoptotic rpL3 gene. PMID: 27835895
- nucleolar stress induced by 5-fluorouracil in colon cancer cells devoid of p53 leads to the activation of ribosomal protein L3 as proapoptotic factor PMID: 27385096
- We found that uL3 down-regulation correlates positively with multidrug resistance. Restoration of the uL3 protein level re-sensitized the resistant cells to the drug by regulating the reactive oxygen species (ROS) levels, glutathione content, glutamate release, and cystine uptake. PMID: 28273808
- rpL3 participates in the cell response to chemotherapy acting as a critical regulator of cell cycle, apoptosis and DNA repair, by modulating p21 expression PMID: 25473889
- The rpL3 is able to modulate the protein amounts of p21 through a novel pathway independent from p53 involving Sp1 and NPM. PMID: 23255119
- NPM and KHSRP are two newly identified proteins involved in the regulation of rpL3 gene expression via alternative pre-mRNA splicing. PMID: 21705779
- working model in which rpL3 recruits hnRNP H1 and, through cooperation with other splicing factors, promotes selection of the alternative splice site PMID: 20100605
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亞細胞定位：Nucleus, nucleolus. Cytoplasm.
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蛋白家族：Universal ribosomal protein uL3 family
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數據庫鏈接：
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