RPH3AL Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q9UNE2
基因名：

RPH3AL
別名：

Gm1753 antibody; No C2 domains protein antibody; Noc2 antibody; Rab effector Noc2 antibody; Rabphilin 3A-like (without C2 domains) antibody; Rabphilin 3A-like antibody; Rabphilin-3A-like protein antibody; RPH3AL antibody; RPH3L_HUMAN antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human NOC2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Acts as a potential RAB3B effector protein in epithelial cells.
基因功能參考文獻：
1. genetic alterations in RPH3AL are associated with aggressive behavior of breast cancers and with short survival of patients. PMID: 26070152
2. Mutations of rabphillin-3A-like gene is associated with colorectal cancers PMID: 12375017
3. Noc2 may function as a Rab3B effector protein in epithelial cells. PMID: 15003533
亞細胞定位：

Cytoplasm. Cytoplasmic vesicle, secretory vesicle membrane. Note=Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells.
組織特異性：

Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
數(shù)據(jù)庫鏈接：

HGNC: 10296

OMIM: 604881

KEGG: hsa:9501

STRING: 9606.ENSP00000328977

UniGene: Hs.651925

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