RNGTT Antibody
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中文名稱：RNGTT兔多克隆抗體
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貨號：CSB-PA526449ESR2HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: RNGTT antibody at 1.42µg/ml + THP-1 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 69, 67, 53, 62 kDa
Observed band size: 69 kDa -
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA526449ESR2HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) RNGTT Polyclonal antibody
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Uniprot No.：
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基因名：RNGTT
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別名：CAP1A antibody; GTase antibody; GTP--RNA guanylyltransferase antibody; hCAP antibody; HCAP1 antibody; HcE antibody; HCE1 antibody; MCE1 antibody; MCE1_HUMAN antibody; mRNA 5''-triphosphatase antibody; mRNA capping enzyme antibody; mRNA guanyltransferase antibody; mRNA guanylyltransferase antibody; Polynucleotide 5' trisphosphatase antibody; RNA guanylyltransferase and 5' phosphatase antibody; RNGTT antibody; TPase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human mRNA-capping enzyme protein (1-260AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
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基因功能參考文獻：
- c-Myc deregulation induces mRNA capping enzyme dependency in tumor cells. PMID: 27756891
- These results identify a new domain of CE that is specific to its function in cytoplasmic capping, and a new role for Nck1 in regulating gene expression through its role as the scaffold for assembly of the cytoplasmic capping complex. PMID: 25137142
- Our biochemical studies provide the first insight that MZP can inhibit the formation of the RNA cap structure catalyzed by HCE. PMID: 23349942
- Data show that human capping enzyme residues 229-567 comprise the minimum enzymatically active human GTase (hGTase) domain and determine the structure by X-ray crystallography. PMID: 21636784
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亞細胞定位：Nucleus.
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蛋白家族：Non-receptor class of the protein-tyrosine phosphatase family; Eukaryotic GTase family
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組織特異性：Isoform 1 and isoform 4 (at a lesser extent) are expressed in cerebrum, cerebellum, thyroid, lung, heart, liver, kidney, spleen, large intestine, testis, skin and muscle.
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數(shù)據(jù)庫鏈接：
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